Anti Cardiolipin IgGAM Screening Kit
Autoantibodies against cardiolipin are found in a wide range of conditions such as systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). This kit is designed for the qualitative screening of IgG, A and M autoantibodies against cardiolipin present in human serum. Samples testing positive in this screening assay should be confirmed by a quantitative measurement of the individual classes (IgG, IgA and IgM) of anticardiolipin autoantibody, using e.g. BINDAZYME Anticardiolipin IgG, IgA and IgM kits.
Antigen
The microwells are precoated with purifed bovine cardiolipin and ß2 glycoprotein (cofactor).
Result Interpretation
| Result | Interpretation | Action |
|---|---|---|
| OD equal to, or greater than cut-off control
| Suspected of having one or a combination of anticardiolipin antibodies | Test on each of the quantitative assays
|
| OD less than cut-off control | Negative | Report as negative |
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